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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56545507050e655e9f605914b20caafb37cc3aa82376d693049da4432b55ca95' 
  AND token = 'adDBEc8M/ioRUd1W8s6EBJ15QPcZv8aPwrRPVes9MVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}