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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3788d1c5ff19fa44b2b8bcdfef483e3b0689b641a012d3e173e8908eb5af6d61' 
  AND token = 'aQ8GMsPnN8eTq54L3lR+rQYqLEIdFcZ4dP4uvZsiwcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}