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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8e02b706ec6c862a576e846927cecb7587bde6fa491428ed7e551c38bdd877' 
  AND token = 'lP2DTHb6h+cg4IuLMGA6hT7oFkPjTOqdJMu1PwSbw9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}