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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2cfe9d56de12e19876355808104f7821345026d2de2ca58e1d8e1c56c2ee9fa' 
  AND token = '2JbuWx9Sw0jd0mF0BWcwf1jjcOt70RYexMK5Z7FmNpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}