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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e207e25d898d3a6a016bfff32fa157bf87b63c563d059a695f403731e90073' 
  AND token = 'C7Dc/d3vHpXJcDz19u1J8PbeA318VlZHhJXpkdw9sjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}