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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd313d69b7e0efad016f4523f023ce6cd8a7aebfd4df5a67107248e2dff5351a6' 
  AND token = 'EX667FKi84fdxywbzsWdRKk/V3b/uLr0bCvxD/wehOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}