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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bf84a855334a28dcf0b21c9c1f14d50cef3a1663f531903598239be8e62481a' 
  AND token = '0T1A9mGXiIbDtiqTfrv3+xBrDKwwG7IYA1yc/h8mf1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}