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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f6a538455e154cce75e51806a1d12fd4467c06a542c1a7a8825f91e4b0814d' 
  AND token = 'Eb3tfJ6UWXMTgGFBOjBIpU2djo+9bHktl7HyL1pz0d4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}