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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c9efa86d778de6279097e0cf644731b0ca355ed9f370ca3c828eb18a198c46' 
  AND token = 'bH/esPusYULqJtE69/D/otjoFsuuli5XjQnu+LzLtoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}