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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cd3a53280f365ed321da7c6b2125a80a4bc04f9385ddc72dde38782f2ece7d' 
  AND token = '08IGuBQrzOvtGQXFL3DASerm5ihsAoQvTN/14bt6YXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}