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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca66b6f72c8e7ac6137cfee26ad8a8ff1086f680b04c9ff2ae7e0e022be3297' 
  AND token = 'slga2yYifkvy1d1DlFAV6/D/nKyCpYfejfsCX+riPwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}