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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c29d98c6bd16b3a600d19beae34b9c46c1d87620e555f8771e13d0f6d16614' 
  AND token = 'jopmqmav1BlgIbWhBV52OhAtiuF5BQiaf1CIu5DUn+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}