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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222d5e4c0ebf284d6da9e6400d2a36ad1346469171fb7a340bd131ec7129a527' 
  AND token = 'bOSz73tlewMp/AZYstMmhSWqOFRQr70KvE9b3ALAlXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}