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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f754a48ea698b808ad38cc8defb81d88ade7bffb04932ba1d7e1b0246eccc468' 
  AND token = '2zxnLc6BOvJteqatkZZQ3AynjKOPLUc+1RrGr6nefBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}