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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74afe3ec8f39f36529a6608618cf1b64829367edcb916ec32262c569ec746302' 
  AND token = 'z4JRYW5MtUqYGHIR9zElWKTLZn0NG/J7INb2eqWo46w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}