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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b300903ebb2ad0a635ed23e4a233fcfdca4dfbea75f703354ad39f4901a101' 
  AND token = 'a6ubagALBTxRp+wKX/JkS3AiXne6wNfY+J4xvst5TX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}