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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15829c8fb76430216875e856b4aaaa8200a3377574bc29a647675207ad0c5d58' 
  AND token = 'XfImRONiIlH+iHeL90SKGDCd12YGYS76BS0bUKRh9tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}