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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd73989b0ce6b2631c58158a3c4ce4b5de3916e3378672be03de84467f0c8dc55' 
  AND token = '8sG3WGTb2fDq2PYp2iaFZ6t+YBzvSmQGjxSQ+xTRxzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}