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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f61d9ff9f1a400bdf8266d983aee3a6df951edc3e8bf78731f7141b69108677' 
  AND token = 'cfJJgXBthGE3uQTChbu5lTGN+7ZdBjPSfsA9i+exAXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}