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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4d9d757ccce6d22a6807e9c89202553213934c8eeb8a991ec0137aa01ba045' 
  AND token = 'u4MdjSLs0aSnU2BXdtDF06o8iQFesAkxQAo5Bao5++o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}