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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ebe0e53ae5b79a1aefb1abea6705a134d653700a65afa97e462d7a3b456e00' 
  AND token = 'cSGFjzHrbrJIQL2UcDk/D2kKu4aVQoUlmDHyyJcHczY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}