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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80165df5f744d6493c6847634443a4f1695369e5c9326aed882e2476a82ad95e' 
  AND token = '97xdvjGtk5n+Ciz7G5YVG9tSJkg1zE0WFBUr5XqQyi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}