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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc3ec59437417dd70aacbf8bd0a7e12c44895d01c951573fbde219a45d3b9dca' 
  AND token = 'Tu8wsl0/jpxt8sbNBGqo2BRssqsB9xkzSgOjlrH9V9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}