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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad075b82a66fd705d011a60e89f6c39b9cff9010e846aff5474766b065a8f405' 
  AND token = 'RzVeIXO42XSgH8zCIWYmCUk0BeIw9augYu5D9uTelgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}