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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21846d4b9343a0e0495283a3965e8d9233ba085b5c609da89c3227d3b3751472' 
  AND token = 'lhyUwIdW3Alf77F6dT1Joj7mBDcAV6ttsmM7XbcP35s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}