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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487a93612e24ff75f227747bcbd79643a8da9b1bc21f72dc7cf760dd89336397' 
  AND token = 'vjG9YIbyoUx5Z8QWdSY5bt/nNpkshHukdM6T0aml/fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}