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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857e609347798c3f3cdca1250d2ed1cfcbf309d20e0d48f496d488e420ee50ba' 
  AND token = 'YD+GCnp9aH/nMWR0LJVtz4LTq2jL/J4Hl0lMYHsLLjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}