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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292d6c924a17449d4b147fbea2ba39ef9474a061049e7bf10bfe5505d39a545a' 
  AND token = 'Enams1qRs/zzlSz/qmEQ1KeMw9jBzRXk662Z4nnE5Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}