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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fcd271f361e9382d7dfe11978e2e6b4f983a04df08c40ca78a1e60eab8491eb' 
  AND token = 'nsrJR/txKXc/KTZlxYkaTUjQ0q+anFVYzHOtLH1qjXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}