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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a4907b02da5d70cb557f7fa9227f940f2569c823c7e0b93f5921dcee85050f' 
  AND token = 'OhAUqnn4H3uR6RSxjtNwghEPxbfHVUnYa83TBNuAPdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}