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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a41b489c76d2a78d883487a1210b674c078930469d57fd5847750b160f4b9a' 
  AND token = 'U3kTUOvmJVC8uwMVqmniOYgJ8N60X+1//9oLJRbkUos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}