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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6b5a4ab3e9b49618af54c27e6284afd1120363f0e53305f08e0f37eab8785f' 
  AND token = 'V2tt9KpekNXA7txCF20iL5GOTRyvn9YZiXTs/h/TN1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}