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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c999c9d817ce126403a83ba706020343596724b7d7c32e8e3ec0c12d8c54df' 
  AND token = '75XnARFCTVDRgdiXfarOHvN/KOOIHe1mIS50Llj6n88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}