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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e517e07f21d9035876088e736faaac3cef94c8245571c78e075249d0f92740' 
  AND token = 'eTtPP+gRU6MKBbarhZl8kn/uLWL7GlvmJVeEWUTZIi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}