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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e701a4cb12dfabf79e054f210a9525385892cfbec7be8133049b4e4c201959' 
  AND token = '5mEdYpJJNJ/+05slaDtn39dIqZ6MDIlm5vo7aefgRSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}