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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f62c9f5395a2cbcfd1c596a0eb702f37ef05c4e110977186d867f29016daed1' 
  AND token = 'T1ugB8dSUJPO7OhkbtN1CdEP3ZVWK+ungUlkQOpT6Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}