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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12333240984d5a4e7ff2d942ef401d63446dd6833062b48d919938cda4b495b' 
  AND token = 'u0M/nEfPtS4KAwyKj5kns3PzKO3JNGPE+LCnAz1h0Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}