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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97cff95a111cfaa2d9d49151dc5f0bc5402ccc60b8e61ede97e3794ec9e590aa' 
  AND token = 'pZw9dC4bHHQlZ0zOwOzVWdAzDEw5ikBvz+z6AbF09oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}