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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a836ff643ea74125907032d00fb9cf4e6e3b824ec68de5ec4a68e0f5cd86a437' 
  AND token = 'imansiUpl2uruzmFP1qJi+Afxpv9YW2wchv3dgEgCWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}