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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483f04946af07541ce2bd3ee44f83ae61bab6c886019df0be308e671006f7ef6' 
  AND token = 'CCIwv2XBKxB9lmcHkT0vX58I0ACPSjybSBh8yww9GZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}