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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241c28bbfd3bfe8d50430085b85dc37489b56dd1d0ee71bf36374b3f988b8fa9' 
  AND token = 'ldZzJFW8+LmQ3RRrfhV4ioBB0gS42DC9Mgi4bthq3fU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}