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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f60a8ae01f76ff6d6cd41aeb19e5e294b0a104f42184a185b46e910249c2b3b' 
  AND token = 'y8HBU2QiA8vpFKhzAzeZzgbGJVj9D5GRkDS8nEEbb5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}