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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d4855ef527ed8c4f81568ad9f1cf69267e69bc98582cf5c26c629f5331e81e' 
  AND token = 'PZpeSsHRtFZm62iWSbAnTbhhFEG9vx3+XIwwXUJF1Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}