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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667f5a63e83ede56d011b76643201070e7c668d97b09f3aac03e3ccd3c624d44' 
  AND token = 'gvx3COxumpd/YDuPB2uZClPgAaPSAJilG4VFiCMnKi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}