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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1e5723be7f291e2c94cf2c99a3ba5301dfa871ab0e978d2071179015bb8cf3' 
  AND token = 'GnXkKLIheyAv6PpKIVAtK2xM2AaiIADRo/ybvGig9O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}