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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6b93d79ac096f21dfef8c42e4e2031ff8a3f51eecd39f2a328b72123b63a90' 
  AND token = 'YTnoE0/iLA9xmDP2EEVYZ+Bw8/8MIY6MfJ6FAHT7dzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}