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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc19895160c46c7f8bb41e4c6da70047952d67706284fbd688e390a4ab5b2de' 
  AND token = 'epBMpmnJgN4szj4PKsWk8MOlyg0tTT8vCr/O7Lf7ID0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}