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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2fecfa8d45073e112c0d579c3f9546f0ed81a748aaa06094ccd40a2b4364036' 
  AND token = 'HQgzKC9R9f2qgaqpnMV0AVWdSimoxwVAItNRiCTkNMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}