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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdd01709bbd9c8696a2e5624167d8476e3496b903d366b9f328a736b13fa566e' 
  AND token = 'P55E46DcevFJlzMuZhgaW/qypJrMIEpWtyWqbtHL8Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}