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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a55c4e3f0226f7220d9b799c9f5d08b34746ba020af653c2ac4e2caba920b1' 
  AND token = 'EX2oU+Q8q1dcOPxarha03SIM/BsD7awT0+x43auwWmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}